Polynucleotide treatment in Croydon, London
Personalised treatment for skin quality and hydration
Book a consultation at our Croydon aesthetic clinic to discuss fine lines, skin texture, elasticity, hydration and under-eye concerns. Every polynucleotide treatment plan is tailored to your skin concerns, medical history and individual goals.
Understanding polynucleotide treatment
Polynucleotides are injectable preparations containing purified chains of nucleotides, which are components of DNA. They are used in aesthetic medicine with the aim of supporting hydration and overall skin quality. Research is also exploring their potential effects on tissue remodelling and regeneration.
Unlike traditional dermal fillers, polynucleotides are generally not used primarily to add volume or reshape facial features. Treatment focuses more on skin quality, including texture, elasticity, hydration and the appearance of fine lines.
Polynucleotide products may be used on areas such as the face, around the eyes, neck and other selected areas depending on the specific product and individual concerns. Some polynucleotide products used in aesthetic medicine are derived from highly purified DNA of fish origin, so the source and ingredients of the specific product should be discussed during consultation.
Current research suggests potential improvements in skin texture, elasticity, hydration and wrinkles, although evidence remains limited and treatment protocols vary between products and studies. A consultation is therefore important to establish realistic expectations and determine whether treatment is appropriate.
Key benefits of polynucleotide treatment
Improved skin hydration
Some clinical studies have reported improvements in skin hydration following polynucleotide treatment, although results vary between products and individuals.
Smoother-looking texture
Treatment may help improve the appearance of rough or uneven skin as overall skin quality changes gradually over time.
Improved elasticity
Research has reported improvements in measures of skin elasticity in some patients following a course of polynucleotide treatment.
Softer fine lines
Fine superficial lines may appear less noticeable as hydration, elasticity and overall skin condition improve.
Under-eye skin support
Selected polynucleotide products may be considered for fine lines, texture and skin-quality concerns affecting the delicate under-eye area.
Skin quality-focused approach
Polynucleotides are generally used to support skin condition rather than provide the targeted volume or contour associated with traditional dermal fillers.
How do polynucleotides work?
Polynucleotides are chains made from nucleotides, the building blocks of DNA. When used in aesthetic medicine, purified polynucleotide formulations are injected into selected areas of the skin.
Skin hydration
Polynucleotide formulations may help support an environment within the skin that contributes to improved hydration and skin quality.
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Tissue environment
Research is exploring how polynucleotides may influence cellular activity and tissue remodelling, although the precise aesthetic mechanisms are still being investigated.
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Skin elasticity
Some studies have reported measurable improvements in elasticity and firmness following a treatment course.
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Gradual improvement
Polynucleotides are not intended to create an immediate filler-like result. Visible changes tend to develop gradually during the weeks following treatment.
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Product-specific effects
Polynucleotide products vary in concentration, formulation and intended treatment area. Results from one product or protocol cannot automatically be applied to every polynucleotide treatment.
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What concerns can polynucleotides address?
Fine lines
Polynucleotide treatment may help reduce the appearance of fine lines as overall skin quality changes gradually following treatment.
Under-eye skin quality
Selected polynucleotide products may be considered for fine lines, texture and skin-quality concerns around the delicate under-eye area.
Uneven skin texture
Treatment may be considered when the skin feels less smooth or when improving overall texture is an important treatment goal.
Dehydrated skin
Polynucleotides may support skin hydration, helping skin that appears dry or tired feel more supple over time.
Loss of elasticity
Clinical research has reported improvements in measures of elasticity following some polynucleotide treatments, although individual responses can vary. PubMed
Dull-looking skin
Improvements in hydration and overall skin quality may help the complexion appear smoother, fresher and more radiant over time.
What happens during your consultation and treatment?
01. Consultation
We start by discussing your skin concerns, treatment goals and relevant medical history. Your practitioner will explain whether polynucleotide treatment may be suitable.
02. Skin assessment
Your skin quality, texture, treatment areas and individual concerns are assessed carefully so recommendations can be tailored to your needs.
03. Treatment planning
If treatment is appropriate, your practitioner will explain the product, injection areas, expected outcomes, possible side effects and recommended treatment schedule before you proceed.
04. Aftercare
You will receive personalised aftercare guidance and information about what to expect as temporary redness, swelling or injection-site marks settle.
Polynucleotides vs skin boosters and Profhilo
Polynucleotides, skin boosters and Profhilo are all used with the aim of improving skin quality, but their formulations and treatment approaches differ.
| Polynucleotides | Skin boosters | Profhilo | |
|---|---|---|---|
| Main focus | Skin quality and hydration | Hydration and skin quality | Hydration, elasticity and skin quality |
| Main ingredient | Purified nucleotide chains | Often hyaluronic acid | Hybrid hyaluronic acid complexes |
| Facial volume | Not the primary goal | Usually minimal | Not the primary goal |
| Under-eye use | Selected products may be used | Depends on product | Product and area dependent |
| Treatment course | Often a course of sessions | Often a course of sessions | Commonly two initial sessions |
| Treatment choice | Based on skin and area | Based on skin concerns | Based on skin quality and laxity |
How to prepare for polynucleotide treatment
Your practitioner will provide personalised advice according to your medical history, skin condition and the specific polynucleotide product being considered.
Before your appointment
- Tell your practitioner about previous injectable treatments
- Discuss relevant medical conditions and allergies
- Provide details of medicines and supplements you take
- Mention active infection, irritation or inflammation
- Discuss any recent facial or aesthetic procedures
- Ask about the ingredients and source of the product being used
Some polynucleotide products used in aesthetic medicine are derived from highly purified fish DNA. If you have relevant allergies or sensitivities, this should be discussed before treatment.
Do not stop prescribed medication unless advised by the healthcare professional responsible for your care.
Results, recovery and aftercare
If polynucleotide treatment is recommended, your practitioner will explain what to expect afterwards, including the likely results timeline, recovery and follow-up.
Polynucleotides are not intended to provide an immediate volumising effect. Changes in hydration, texture and overall skin quality generally develop gradually during the weeks following treatment. Individual results and timelines vary.
Results are temporary and can vary depending on the product, treatment area, initial skin condition and individual response. Some research has reported improvements persisting for several months, but long-term evidence remains limited. PubMed
Downtime is generally limited. Temporary redness, swelling, tenderness, bruising or small raised areas at the injection sites may occur and usually reduce as the treated area settles.
Polynucleotide treatment is often performed as a course rather than a single appointment. Published protocols vary, with studies using different numbers of sessions and treatment intervals. Your practitioner will recommend a plan based on the product and treatment area. PubMed
Your practitioner will provide personalised advice about caring for the treatment area and activities to avoid afterwards. Contact the clinic if you experience symptoms that concern you.
Are polynucleotides suitable for you?
A consultation can help determine whether polynucleotides may be suitable for your skin concerns, desired outcome, medical history and individual goals.
You may want a consultation if you:
- Are concerned about fine lines or skin texture
- Have noticed changes in skin elasticity
- Want advice about under-eye skin quality
- Would like to improve hydration and overall skin condition
- Prefer treatment without targeted facial volumising
Treatment may not be suitable if you:
- Are pregnant or currently breastfeeding
- Have infection or inflammation in the treatment area
- Have allergies relevant to the proposed product
- Take medicines that may affect treatment suitability
- Have a medical history requiring further assessment
Your practitioner will review your medical history, medications, allergies, skin condition and proposed product to determine whether treatment is appropriate. Suitability is assessed individually during consultation.
Which areas can be treated with polynucleotides?
The appropriate treatment area depends on the specific product, its intended use and your individual skin concerns.
Under-eye area
Selected polynucleotide products are used for fine lines, texture and general skin-quality concerns around the eyes.
Face
Facial treatment may be considered where fine lines, texture, hydration or overall skin quality are the main concerns.
Neck
Polynucleotides may be considered for selected skin-quality concerns affecting the neck, depending on the product being used.
Décolletage
Some clinical protocols include the décolletage where texture and visible skin-quality changes are being addressed.
Hands
Selected products and protocols may be considered for visible changes in skin quality affecting the backs of the hands.
Other selected areas
Published expert guidance has discussed use across the face, periocular region, neck, décolletage, hands, scalp and stretch marks. However, the appropriate product and evidence differ by indication.
Why choose Wellbeing Aesthetic for polynucleotides?
Personalised, safety-focused polynucleotide care planned around your skin quality, treatment area and individual goals.
- Personalised Treatment Planning
- Detailed Skin Assessment
- Regenerative Skin Approach
- Safety-Focused Care
- Treatment Area Assessment
- Aftercare & Follow-Up Support
Polynucleotide treatment at our Croydon clinic
Wellbeing Aesthetic provides personalised aesthetic and skin treatments from its clinic in Croydon, South London.
The clinic’s wider approach is consultation-led, with treatment recommendations based on your skin, health and individual goals rather than using the same approach for every patient.
Your polynucleotide treatment journey begins with an assessment of your skin quality, texture, hydration, treatment area, medical history and individual goals.
This allows your practitioner to determine whether polynucleotides are appropriate or whether a skin booster, Profhilo or another treatment may better suit your concerns.
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Want to improve your skin quality?
Book a personalised consultation at Wellbeing Aesthetic in Croydon to discuss your skin concerns, understand how polynucleotides differ from other injectable treatments and find out whether they may be suitable for you.
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Frequently Asked Questions
What are polynucleotides?
Polynucleotides are chains of nucleotides, which are components of DNA. Injectable polynucleotide products are used in aesthetic medicine to support skin quality, hydration and tissue condition rather than primarily adding facial volume.
How do polynucleotides work?
Research suggests polynucleotides may influence the skin environment in ways that support hydration and tissue remodelling. However, the precise aesthetic effects vary between formulations, and further high-quality clinical research is still needed.
Can polynucleotides be used under the eyes?
Yes, selected products and treatment approaches may be used for concerns around the eye area, particularly fine lines and skin quality. Recent research has reported improvements in periorbital appearance, although suitability depends on individual anatomy and concerns.
Are polynucleotides the same as skin boosters?
No. Both are injectable skin-quality treatments, but they contain different substances and work in different ways. Many skin boosters are based primarily on hyaluronic acid, while polynucleotide treatments contain purified nucleotide chains.
How many polynucleotide treatments will I need?
The recommended number varies according to the product, treatment area and individual goals. Many clinical protocols use a short course of treatment followed by assessment, rather than relying on one treatment for everyone.
How quickly can I see results?
Polynucleotide results develop gradually. Changes in hydration, texture or skin quality may become more noticeable over several weeks and through the treatment course rather than immediately after injection.
Is there any downtime after polynucleotides?
Downtime is usually limited, although temporary swelling, redness, tenderness, bruising or small bumps can occur at injection sites. Reviews of current studies generally report mild and temporary treatment-related effects.
Are polynucleotides suitable for everyone?
No. Pregnancy or breastfeeding, active skin problems, allergies, medicines and certain medical conditions may affect suitability. The ingredients and source of the specific product should also be considered during your consultation.
